For US Residents Only

Prurigo Nodularis
Intense. Difficult to live with. More than skin deep. Not going to rule my life.

Prurigo Nodularis
An Unrelenting Itch

Getting people to understand the level of distress you experience with PN can become difficult, which of course only adds to your frustration. But the itch from PN is among the most severe of any dermatological conditions.

Physical Symptoms

  • Painful stinging itch on arms, legs, upper back, and/or abdomen.
  • Raised bumps or nodules on areas of the skin accessible to scratching.
  • Persistent itch that lasts at least 6 weeks.
  • Continued scratching may result in the bumps you see on your skin and can cause burning, stinging, bleeding, and scarring.

Do these symptoms sound familiar to you?

Download this symptom tracker to keep tabs on which PN symptoms you have, how severe they are, how they impact your life, and how they change over time.

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Prurigo Nodularis
An Itch that Impacts YOU

PN symptoms can also deeply impact your mental health and your daily lifestyle.

Psychological Impact

  • PN symptoms can make sleeping difficult and cause you to experience chronic fatigue.
  • PN patients are more likely to develop depression and anxiety than those without PN.
  • Visible nodules and bleeding can be troubling for patients.
  • Some PN patients are told that they are to blame for their PN symptoms or made to feel
    like the disease is all in their head.

Lifestyle Impact

  • PN can negatively impact a patient’s ability to carry out daily activities.
  • Patients are often absent from work more than colleagues.
  • The condition also causes patients to retire from work.
  • Patients avoid social activities due to judgement of their skin's appearance.

Prurigo Nodularis
Caused IN PART by Inflammation

Although the cause of Prurigo Nodularis is not fully understood, evolving research suggests an abnormal relationship between the skin, nervous system, and immune system can lead to unwanted inflammation and itch. This results in signs and symptoms you see and feel.

Prurigo Nodularis

That’s part of the reason why it’s widely misunderstood and
frequently misdiagnosed. Curious about who is impacted by PN?

~311k PN patients in the US
African Americans are disproportionately
impacted by PN

Prurigo Nodularis

Nearly 45% of PN patients in the US have uncontrolled symptoms, despite using topical therapies. But there may be hope due to various clinical trials underway that are testing possible treatment options.

Learn More About Ways to Manage PN

Use this discussion guide to begin a conversation with your doctor and see what options exist for PN management.

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Have you been diagnosed with Prurigo Nodularis by a physician?